Video files for 'Large CRISPR-Cas-induced deletions in the oxamniquine resistance locus of the human parasite Schistosoma mansoni ' SankaranarayananGeetha CoghlanAvril DriguezPatrick LotkowskaMagda E. SandersMandy HolroydNancy TraceyAlan BerrimanMatthew RinaldiGabriel 2020 Video files for Wellcome Open Research article 'Large CRISPR-Cas-induced deletions in the oxamniquine resistance locus of the human parasite <i>Schistosoma mansoni</i> '<div><br></div><div><div>Movie 1. Serial optical sections of a <i>S. mansoni </i>male adult worm transfected with fluorescently labelled Cas9-gRNA (ATTO™ 550 signal in red), fixed and DAPI-stained (DAPI signal in aqua blue). Scale bar: 100 µm.</div><div><br></div><div>Movie 2. Serial optical sections of a <i>S. mansoni</i> male adult worm transfected with fluorescently labelled Cas9-gRNA (ATTO™ 550 signal in red), fixed and DAPI-stained (DAPI signal in aqua blue). In these series of optical sections, the anterior end of the worm is observed. Scale bar: 100 µm. </div><div><br></div><div>Movie 3. Serial optical sections of a <i>S. mansoni</i> female adult worm transfected with fluorescently labelled Cas9-gRNA (ATTO™ 550 signal in red), fixed and DAPI-stained (DAPI signal in aqua blue). In these series of optical sections, the anterior end of the worm is observed. Scale bar: 100 µm.</div><div><br></div><div>Movie 4. Serial optical sections of a <i>S. mansoni</i> sporocyst transfected with fluorescently labelled Cas9-gRNA (ATTO™ 550 signal in red), fixed and DAPI-stained (DAPI signal in aqua blue). Scale bar: 25 µm. </div></div><div><br></div>